Autism as a Neuroinflammation

• Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism
• Autism subtype brain allergy Clin Therapeutics May 2013
• Autism, brain inflammation, J Neuroinflammation 2012
• TCT Brain Inflammation Neuropsychiatric Disorders
• The “missing link” in autoimmunity and autism, Autoimm Rev 2013

Dysfunction of immune system in Autism

• autism, immune response
• Autism, innate immunity
• Elevated imm resp in autistic brains
• IgG, autism
• IL-6, autism mouse phenotype
• IL-9, mast cells
• Ileal lymphadenopathy-Autism Research
• Immune response in autism
• Immune response in autistic children 2009
• Immunostimulation Adverse Effects
• Li Chauhan 2009 Elevated immune response in autistic brains Th1
• Maternal brain Abs
• Mother brain antibodies-autism
• mucosal mast cells, inflammation
• NT, mast cells
• Scheid UC and neurol sx Eur J Neurol 2007
• Serum chemokines, autism
• Singer 2009 prenatal maternal antibodies autistic traits murine model
• Wei 2009 genetics in inflammatory microglia LPS cytokines

Neurotensin is neurotoxic (παρουσιάζεται αυξημένη στον ορό των αυτιστικών παιδιών)

• Autism, neurotensin-J Neuroinflamm 2010
• Neurotensin, neurotoxicity

Luteolin and Quercetin are anti-inflamantory substances and neuroprotective flavonoids

• Flavonoid quercetin protects against swimming stress-induced changes in oxidative biomarkers in the hypothalamus of rats.
• Flavonoids, Pharm Rev 2000
• Flavonols inhibit mast cells cytokines Br J Pharmacy 
• Luteolin inhibits MS peripheral leukocytes
• Luteolin protects dopaminegic neurons
• Luteolin protects microglia
• Luteolin reduces microglia IL-6
• Luteolin, anxiolytic
• Luteolin, brain transcriptome
• Luteolin, macrophages and LPS from P.intermedia
• Luteolin, spatial memory
• Luteolin, T cells, mast cells BJP 2008
• Quercetin protects against water swim
• Quercetin prrotects brain
• Quercetin, brain anti-oxidant

Luteolin could help some groups of Autism patients

• Autism, basis for NeuroProtek in Autism Science Digest 2010
• Autism, Neuroprotek pilot, Clin Therapeutics May 2013
• Neurotensin for autism
• Theoharides Autism, basis NeuroProtek in Autism Science Digest 2010

Undesirable interactions of drug and food supplements for Autism

• Autism, extracellular mit, suramin, J Clin Psychopharm 8-2013
• Theoharides drug interactions
• Theoharides Drug-supplement Interactions Autism Digest 

Press

• GreekReporter
• Health Daily